BDBM50598647 CHEMBL5174941

SMILES C[C@@H](O)[C@H](NC(=O)[C@@H]1CCCCNC(=O)CCCCCC(=O)NCCCC[C@H](NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCNC(=S)NCCC(O)=O)C(=O)N1)C(N)=O

InChI Key InChIKey=VSJUIMNSDMYDDW-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50598647   

TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50598647(CHEMBL5174941)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of GST-tagged SIRT5 desuccinylase activity (unknown origin) incubated for 5 mins by HPLC based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50598647(CHEMBL5174941)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of His6-tagged SIRT2 (unknown origin) desuccinylase activity incubated for 12 mins by HPLC based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50598647(CHEMBL5174941)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of His6-tagged SIRT1 (unknown origin) desuccinylase activity incubated for 10 mins by HPLC based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50598647(CHEMBL5174941)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of His6-tagged SIRT3 (unknown origin) desuccinylase activity incubated for 10 mins by HPLC based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-6(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50598647(CHEMBL5174941)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of His6-tagged SIRT6 (unknown origin) desuccinylase activity incubated for 12 mins by HPLC based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed