BDBM50598697 CHEMBL5179337

SMILES COc1cc([C@@H](C)C(=O)N2CC[C@]3(C2)CCc2cc(c(C)nc2N3)-c2ncccn2)c(Cl)cn1

InChI Key InChIKey=AHFRNFYONJRGRW-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50598697   

TargetMelanocortin receptor 4(Human)
Arrival Discovery

Curated by ChEMBL
LigandPNGBDBM50598697(CHEMBL5179337 | US12187727, Example 64)
Affinity DataKi:  0.25nMAssay Description:Displacement of [125I]-[Nle4-D-phe7]-alpha-MSH from to human MC4R expressed in CHO cells incubated for 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetMelanocortin receptor 4(Human)
Arrival Discovery

Curated by ChEMBL
LigandPNGBDBM50598697(CHEMBL5179337 | US12187727, Example 64)
Affinity DataKi:  1nMAssay Description:Compounds were solubilized in 100% dimethyl sulfoxide (DMSO) to a concentration of 30 mM. A 10-point intermediate dilution series using half log dilu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent

TargetMelanocortin receptor 4(Human)
Arrival Discovery

Curated by ChEMBL
LigandPNGBDBM50598697(CHEMBL5179337 | US12187727, Example 64)
Affinity DataKi:  94nMAssay Description:Compounds were solubilized in 100% dimethyl sulfoxide (DMSO) to a concentration of 30 mM. A 10-point intermediate dilution series using half log dilu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2025
Entry Details
US Patent