BDBM50599060 CHEMBL5187134

SMILES COc1ccc(cc1C#Cc1cnc2cccnn12)C(=O)Nc1cc(cc(c1)C(F)(F)F)-n1cnc(c1)C1CC1

InChI Key InChIKey=IMRBVWVCTYQNMD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50599060   

TargetTyrosine-protein kinase ABL1(Human)
Oregon Health and Science University

Curated by ChEMBL
LigandPNGBDBM50599060(CHEMBL5187134)
Affinity DataIC50: 116nMAssay Description:Inhibition of recombinant human full-length His-tagged ABL1 cytoplasmic domain expressed in baculovirus expression system using Tyr 02 as substrate m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Oregon Health and Science University

Curated by ChEMBL
LigandPNGBDBM50599060(CHEMBL5187134)
Affinity DataIC50: 710nMAssay Description:Inhibition of recombinant human full-length His-tagged ABL1 T315I mutant cytoplasmic domain expressed in baculovirus infected insect cells using Tyr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed