BDBM50599281 CHEMBL5201386

SMILES CN1C(C(=O)N(C)c2cnc(Nc3ccc(cc3)S(N)(=O)=O)nc12)c1cccc(F)c1

InChI Key InChIKey=CTOWPNFHOQGQNY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50599281   

TargetSerine/threonine-protein kinase 4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50599281(CHEMBL5201386 | US12318398, Compound 11)
Affinity DataIC50: 134nMAssay Description:Inhibition of recombinant full length N-terminal GST -tagged human MST1 expressed in baculovirus infected Sf9 insect cells using KKSRGDYMTMQIG as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHepatocyte growth factor-like protein(Human)
Tarapeutics Science Inc.

US Patent
LigandPNGBDBM50599281(CHEMBL5201386 | US12318398, Compound 11)
Affinity DataIC50: 1.34E+5nMAssay Description:The IC50 values of the compounds against MST1 were determined. The protein kinase MST1 and the substrate were obtained from commercial sources.5.4 μL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2025
Entry Details
US Patent