BDBM50599327 CHEMBL5195321

SMILES CC(C)(C)n1cc(-c2cncc3ccccc23)c2c(N)ncnc12

InChI Key InChIKey=WWCBRVQDHYFJEF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50599327   

TargetEpidermal growth factor receptor(Human)
H. R. Patel Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50599327(CHEMBL5195321)
Affinity DataIC50: 53nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
H. R. Patel Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50599327(CHEMBL5195321)
Affinity DataIC50: 1.62E+3nMAssay Description:Inhibition of wild type EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
H. R. Patel Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50599327(CHEMBL5195321)
Affinity DataIC50: 5.42E+3nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed