BDBM50599339 CHEMBL5179288

SMILES Oc1ccc(cc1-c1nc(NCc2ncccn2)c2ccccc2n1)C#N

InChI Key InChIKey=CEDIAVUISYTDCR-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50599339   

TargetEpidermal growth factor receptor(Human)
Arromax Pharmatech Co. Ltd.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599339BDBM50599339(CHEMBL5179288)
Affinity DataIC50: 630nMAssay Description:Modulation of rat mGlu5 receptor assessed as calcium mobilization by cell based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Arromax Pharmatech Co. Ltd.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599339BDBM50599339(CHEMBL5179288)
Affinity DataIC50: 630nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) by HTRF methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Arromax Pharmatech Co. Ltd.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599339BDBM50599339(CHEMBL5179288)
Affinity DataIC50: 630nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Arromax Pharmatech Co. Ltd.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599339BDBM50599339(CHEMBL5179288)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) in human NCI-H1975 cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Arromax Pharmatech Co. Ltd.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599339BDBM50599339(CHEMBL5179288)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of EGFR L858R/T790M double mutant (unknown origin) in human NCI-H1975 cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed