BDBM50599464 CHEMBL5169662

SMILES Oc1ccc2nc(NC(=O)Nc3ccc(NC(=O)C4CCNCC4)cc3)sc2c1

InChI Key InChIKey=ATNNUKBJZFOVTK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50599464   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50599464(CHEMBL5169662)
Affinity DataIC50: 177nMAssay Description:Inhibition of human N-terminal His6-tagged DYRK1A expressed in Escherichia coli BL21 (DE3) using KKISGRLSPIMTEQ as substrate incubated in presence of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetAlpha-synuclein(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50599464(CHEMBL5169662)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of alpha-syn (unknown origin) aggregation assessed as reduction in fluorescence intensity measured after 24 hrs by ThT flourescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed