BDBM50599486 CHEMBL5199890

SMILES CSc1nnc2ccc(N[C@@H]3CC[C@@H](CC3)Nc3ccnc(n3)C(F)(F)F)nn12

InChI Key InChIKey=GMKXJHWPZHQJQM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50599486   

LigandPNGBDBM50599486(CHEMBL5199890)
Affinity DataIC50: 800nMAssay Description:Inhibition of human MALT1 assessed as cleavage of substrate using fluorescent labeled Ac-LRSR-Rh110 peptide as substrate incubated for 30 mins follow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
LigandPNGBDBM50599486(CHEMBL5199890)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of human MALT1 in human MCF7 cells assessed as MALT1 mediated cleavage of human A20 in cytosol by fluorescence microscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed