BDBM50599961 CHEMBL5198841

SMILES Fc1ccccc1CN1CCC2(CCN(CC2)C(=O)c2ccccc2)C1=O

InChI Key InChIKey=WZLYLUDDONQYEY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50599961   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50599961(CHEMBL5198841 | US20250129073, Compound 31)
Affinity DataIC50: 186nMAssay Description:Inhibition of human RIPK1 incubated for 40 min in presence of ATP by ADP-Glo luminescence kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50599961(CHEMBL5198841 | US20250129073, Compound 31)
Affinity DataIC50: 186nMAssay Description:The compounds were diluted in DMSO and configured into a solution with a final concentration of 10 mM; Dilute RIP1 kinase from 140 ng/μL to 20 ng/μL ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent