BDBM50599962 CHEMBL5187835

SMILES Fc1ccc(F)c(CN2CCC3(CCN(CC3)C(=O)c3ccccc3)C2=O)c1

InChI Key InChIKey=UBVAVSVJDWISIE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50599962   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
China Pharmaceutical University

US Patent
LigandPNGBDBM50599962(CHEMBL5187835 | US20250129073, Compound 34)
Affinity DataIC50: 693nMAssay Description:The compounds were diluted in DMSO and configured into a solution with a final concentration of 10 mM; Dilute RIP1 kinase from 140 ng/μL to 20 ng/μL ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
China Pharmaceutical University

US Patent
LigandPNGBDBM50599962(CHEMBL5187835 | US20250129073, Compound 34)
Affinity DataIC50: 693nMAssay Description:Inhibition of human RIPK1 incubated for 40 min in presence of ATP by ADP-Glo luminescence kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed