BDBM50600045 CHEMBL5198485

SMILES Cc1c(COc2ccc(CNCCC(=O)NO)c(OCc3cccc(c3)C#N)c2)cccc1-c1ccccc1

InChI Key InChIKey=SQCCVGNLDJDQFM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50600045   

TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Hubei Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50600045(CHEMBL5198485)
Affinity DataIC50: 82nMAssay Description:Inhibition of PD-1/PDL1 interaction (unknown origin) in by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Hubei Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50600045(CHEMBL5198485)
Affinity DataIC50: 8.37E+3nMAssay Description:Inhibition of HDAC6 (unknown origin) preincubated for 5 mins followed by substrate addition and measured after 30 mins by fluorescence based micropla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Hubei Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50600045(CHEMBL5198485)
Affinity DataIC50: 8.37E+3nMAssay Description:Inhibition of recombinant human HDAC6 using Boc-Lys-(acetyl)-AMC as substrate incubated for 0.5 hr and measured after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50600045(CHEMBL5198485)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human HDAC1 using Boc-Lys-(acetyl)-AMC as substrate incubated for 0.5 hr and measured after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed