BDBM50600605 CHEMBL5208751

SMILES CCN1CCN(CCCN2CCCN(C(=O)c3ccc(NC(=O)c4ccccc4-c4ccccc4)cc3)c3ccccc23)CC1

InChI Key InChIKey=GGOOYOFDSPJDBT-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50600605   

TargetVasopressin V2 receptor(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50600605(CHEMBL5208751)
Affinity DataKi:  9nMAssay Description:Displacement of conivaptan-red from SNAP-tagged human V2 receptor expressed in HEK293 cells measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetVasopressin V2 receptor(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50600605(CHEMBL5208751)
Affinity DataIC50: 9.20nMAssay Description:Antagonist activity at human V2 receptor expressed in CHO cells assessed as inhibition of vasopressin-induced cAMP accumulation incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetVasopressin V1a receptor(Human)
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50600605(CHEMBL5208751)
Affinity DataKi:  147nMAssay Description:Displacement of [3H]-vasopressin from human V1A receptor expressed in CHO cells membrane by microbeta scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed