BDBM50601059 CHEMBL5200875

SMILES COc1cc2cnnc(N[C@H](C)c3ccccc3)c2cc1OC

InChI Key InChIKey=LWGJMWHSNQUWKR-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50601059   

TargetSon of sevenless homolog 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50601059(CHEMBL5200875)
Affinity DataKi:  637nMAssay Description:Binding affinity to SOS1 (unknown origin) assessed as inhibition constant by HTRF methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSon of sevenless homolog 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50601059(CHEMBL5200875)
Affinity DataKi:  637nMAssay Description:Binding affinity to N-terminal his-TEV-Avi-tagged human recombinant SOS1 expressed in Escherichia coli assessed as inhibition constant incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Mirati Therapeutics

Curated by ChEMBL
LigandPNGBDBM50601059(CHEMBL5200875)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human EGFR in presence of ATP by radiometric HotSpot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed