BDBM50601414 CHEMBL5173945

SMILES COc1ccc(cc1Cl)-c1ocnc1C(=O)NCCCn1cncn1

InChI Key InChIKey=RQFYFNAGNBUGFC-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50601414   

TargetGlycogen synthase kinase-3 alpha(Human)
Hefei University of Technology

Curated by ChEMBL

LigandBDBM50601414(CHEMBL5173945)Copy SMILESCopy InChI

Affinity DataIC50:  10nMAssay Description:Inhibition of human recombinant GSK3alphaMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sidPDB

In DepthDetails PubMedPDB3D Structure (crystal)
Copy BDB DOI
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TargetGlycogen synthase kinase-3 beta(Human)
Massachusetts General Hospital

Curated by ChEMBL

LigandBDBM50601414(CHEMBL5173945)Copy SMILESCopy InChI

Affinity DataIC50:  2.10nMAssay Description:Inhibition of recombinant human GSK-3betaMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sidPDB

In DepthDetails PubMedPDB3D Structure (crystal)
Copy BDB DOI
Copy reaction URL

TargetGlycogen synthase kinase-3 beta(Human)
Massachusetts General Hospital

Curated by ChEMBL

LigandBDBM50601414(CHEMBL5173945)Copy SMILESCopy InChI

Affinity DataIC50:  9nMAssay Description:Inhibition of human recombinant GSK3betaMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sidPDB

In DepthDetails PubMedPDB3D Structure (crystal)
Copy BDB DOI
Copy reaction URL