BDBM50602357 CHEMBL5169821

SMILES ONC(=O)CCCCCCNC(=O)c1ccc(NC(=O)COCCOCCNC(=O)COc2cccc3C(=O)N(C4CCC(=O)NC4=O)C(=O)c23)cc1

InChI Key InChIKey=PTJNYVXLFRBJGN-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50602357   

TargetHistone deacetylase 6(Human)
First Affiliated Hospital of Gannan Medical University

Curated by ChEMBL
LigandPNGBDBM50602357(CHEMBL5169821)
Affinity DataIC50: 27nMAssay Description:Inhibition of human HDAC6More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
First Affiliated Hospital of Gannan Medical University

Curated by ChEMBL
LigandPNGBDBM50602357(CHEMBL5169821)
Affinity DataIC50: 27nMAssay Description:Inhibition of recombinant full length N-terminal GST-tagged human HDAC6 (1 to 1215 residues) using Z-Lys(Ac)-AMC as substrate preincubated for 90 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
First Affiliated Hospital of Gannan Medical University

Curated by ChEMBL
LigandPNGBDBM50602357(CHEMBL5169821)
Affinity DataIC50: 159nMAssay Description:Inhibition of human HDAC3More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50602357(CHEMBL5169821)
Affinity DataIC50: 174nMAssay Description:Inhibition of recombinant full length C-terminal His/Flag-tagged human HDAC1 (1 to 482 residues) using Z-Lys(Ac)-AMC as substrate preincubated for 90...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50602357(CHEMBL5169821)
Affinity DataIC50: 174nMAssay Description:Inhibition of human HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
First Affiliated Hospital of Gannan Medical University

Curated by ChEMBL
LigandPNGBDBM50602357(CHEMBL5169821)
Affinity DataIC50: 248nMAssay Description:Inhibition of human HDAC2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed