BDBM50602870 CHEMBL5192405

SMILES CC(=O)c1cc(C(=O)Nc2cc(CO)cc(-c3cnn(C)c3)c2F)c2cc(O)ccn12

InChI Key InChIKey=VLSSRXAUNKQKKE-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50602870   

TargetCREB-binding protein(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50602870(CHEMBL5192405)
Affinity DataIC50: 6nMAssay Description:Inhibition of C-terminal biotinylated tetra-acetylated histone peptide H4 binding to His6-fused human CBP bromodomain (R1081 to G1197 residues) incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50602870(CHEMBL5192405)
Affinity DataIC50: 7nMAssay Description:Inhibition of C-terminal biotinylated tetra-acetylated histone peptide H4 binding to His6-fused human p300 bromodomain (A1040 to G1161 residues) incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCREB-binding protein(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50602870(CHEMBL5192405)
Affinity DataIC50: 26nMAssay Description:Inhibition of His6-tagged human CBP bromodomain (1081 to 1197 residues) expressed in Escherichia coli BL21 (DE3) incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCREB-binding protein(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50602870(CHEMBL5192405)
Affinity DataIC50: 26nMAssay Description:Binding affinity to CBP (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCREB-binding protein(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50602870(CHEMBL5192405)
Affinity DataKd:  44nMAssay Description:Binding affinity to His6-tagged human CBP bromodomain (1081 to 1197 residues) expressed in Escherichia coli BL21 (DE3) assessed as dissociation const...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetProtein cereblon(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50602870(CHEMBL5192405)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of biotinylated thalidomide binding to CRBN (40 to 442 residues) (unknown origin) incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed