BDBM50602917 CHEMBL5200069

SMILES Clc1ccccc1Oc1ccc(Nc2ncnc3[nH]ccc23)cc1

InChI Key InChIKey=NHZNMMAEOYALKY-UHFFFAOYSA-N

Data  2 IC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50602917   

TargetTau-tubulin kinase 1(Human)
Csic

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50602917BDBM50602917(CHEMBL5200069 | US20250051335, Compound 14)
Affinity DataIC50: 330nMAssay Description:Inhibition of recombinant human TTBK1 using RICDLHDDEEDEAMSITA as substrate incubated for 30 mins in presence of 33P-gamma-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetTau-tubulin kinase 2(Human)
Csic

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50602917BDBM50602917(CHEMBL5200069 | US20250051335, Compound 14)
Affinity DataIC50: 490nMAssay Description:Inhibition of recombinant human TTBK2 using RICDLHDDEEDEAMSITA as substrate incubated for 30 mins in presence of 33P-gamma-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetTau-tubulin kinase 2 [1-450](Human)
Csic

US Patent
LigandChemical structure of BindingDB Monomer ID 50602917BDBM50602917(CHEMBL5200069 | US20250051335, Compound 14)
Affinity DataIC50: 490nMAssay Description:A buffer solution containing the recombinant human enzyme TTBK1 (1-1321) or TTBK2(1-450) (5-20 mU) and 50 mM Tris at pH 7.5, 0.1 mM EGTA, 0.1% p-merc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetTau-tubulin kinase 1(Human)
Csic

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50602917BDBM50602917(CHEMBL5200069 | US20250051335, Compound 14)
Affinity DataIC50: 530nMAssay Description:A buffer solution containing the recombinant human enzyme TTBK1 (1-1321) or TTBK2(1-450) (5-20 mU) and 50 mM Tris at pH 7.5, 0.1 mM EGTA, 0.1% p-merc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent
PDB3D3D Structure (crystal)