BDBM50603719 CHEMBL5176338

SMILES CCCCc1nc(/C=N/Nc2nc(Nc3ccccc3)nc(Nc3ccc(S(N)(=O)=O)cc3)n2)c(Cl)[nH]1

InChI Key InChIKey=UQCVHDWXFYZHIG-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50603719   

TargetCarbonic anhydrase 12(Human)
Tanta University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50603719BDBM50603719(CHEMBL5176338)
Affinity DataKi:  77nMAssay Description:Inhibition of recombinant human CA 12 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetCarbonic anhydrase 9(Human)
Tanta University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50603719BDBM50603719(CHEMBL5176338)
Affinity DataKi:  259nMAssay Description:Inhibition of recombinant human CA 9 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetCarbonic anhydrase 2(Human)
Tanta University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50603719BDBM50603719(CHEMBL5176338)
Affinity DataKi:  367nMAssay Description:Inhibition of recombinant human CA 2 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetCarbonic anhydrase 1(Human)
Tanta University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50603719BDBM50603719(CHEMBL5176338)
Affinity DataKi:  3.64E+3nMAssay Description:Inhibition of recombinant human CA 1 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed