BDBM50603838 CHEMBL5187387

SMILES C[C@H](Nc1nc(N)nc(N)c1C#N)c1nn(-c2cccnc2)c2cc(Cl)ccc12

InChI Key InChIKey=VGSSLTPCGYPSOR-UHFFFAOYSA-N

Data  5 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50603838   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Zhejiang University

Curated by ChEMBL

LigandBDBM50603838(CHEMBL5187387)Copy SMILESCopy InChI

Affinity DataIC50: 2nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2 as substrate incubated for 1 hr in presence of ATP by ADP-Glo assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

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In Depth
Date in BDB:
6/25/2023
Entry Details
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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Zhejiang University

Curated by ChEMBL

LigandBDBM50603838(CHEMBL5187387)Copy SMILESCopy InChI

Affinity DataIC50: 2nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

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In Depth
Date in BDB:
10/11/2025
Entry Details
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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Zhejiang University

Curated by ChEMBL

LigandBDBM50603838(CHEMBL5187387)Copy SMILESCopy InChI

Affinity DataIC50: 2nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2:PS as substrate in presence of ATP measured after 1 hr by ADP-Glo assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

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In Depth
Date in BDB:
12/19/2024
Entry Details
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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Zhejiang University

Curated by ChEMBL

LigandBDBM50603838(CHEMBL5187387)Copy SMILESCopy InChI

Affinity DataIC50: 41nMAssay Description:Inhibition of PI3Kbeta (unknown origin) using PIP2 as substrate incubated for 1 hr in presence of ATP by ADP-Glo assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

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In Depth
Date in BDB:
6/25/2023
Entry Details
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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Zhejiang University

Curated by ChEMBL

LigandBDBM50603838(CHEMBL5187387)Copy SMILESCopy InChI

Affinity DataIC50: 275nMAssay Description:Inhibition of PI3Kgamma (unknown origin) using PIP2 as substrate incubated for 1 hr in presence of ATP by ADP-Glo assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

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In Depth
Date in BDB:
6/25/2023
Entry Details
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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Zhejiang University

Curated by ChEMBL

LigandBDBM50603838(CHEMBL5187387)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate incubated for 1 hr in presence of ATP by ADP-Glo assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

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In Depth
Date in BDB:
6/25/2023
Entry Details
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