BDBM50604033 CHEMBL5182087::US20230312529, Compound 6j

SMILES Cc1cnc(Nc2ccc(N3CCC(N4CCN(C)CC4)CC3)cc2)nc1Nc1ccc2cn[nH]c2c1

InChI Key InChIKey=CLBDTZNPSUWWJD-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50604033   

TargetPlatelet-derived growth factor receptor beta(Human)
Wenzhou Medical University

US Patent
LigandChemical structure of BindingDB Monomer ID 50604033BDBM50604033(CHEMBL5182087 | US20230312529, Compound 6j)
Affinity DataIC50: 12nMAssay Description:The method adopted in the test was Caliper Mobility Shift Assay, which was a detection platform based on the mobility detection technology of microfl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Wenzhou Medical University

US Patent
LigandChemical structure of BindingDB Monomer ID 50604033BDBM50604033(CHEMBL5182087 | US20230312529, Compound 6j)
Affinity DataIC50: 12nMAssay Description:The method adopted in the test was Caliper Mobility Shift Assay, which was a detection platform based on the mobility detection technology of microfl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Wenzhou Medical University

US Patent
LigandChemical structure of BindingDB Monomer ID 50604033BDBM50604033(CHEMBL5182087 | US20230312529, Compound 6j)
Affinity DataIC50: 14nMAssay Description:The method adopted in the test was Caliper Mobility Shift Assay, which was a detection platform based on the mobility detection technology of microfl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor alpha(Human)
Wenzhou Medical University

US Patent
LigandChemical structure of BindingDB Monomer ID 50604033BDBM50604033(CHEMBL5182087 | US20230312529, Compound 6j)
Affinity DataIC50: 15nMAssay Description:The method adopted in the test was Caliper Mobility Shift Assay, which was a detection platform based on the mobility detection technology of microfl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor alpha(Human)
Wenzhou Medical University

US Patent
LigandChemical structure of BindingDB Monomer ID 50604033BDBM50604033(CHEMBL5182087 | US20230312529, Compound 6j)
Affinity DataIC50: 15nMAssay Description:The method adopted in the test was Caliper Mobility Shift Assay, which was a detection platform based on the mobility detection technology of microfl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Wenzhou Medical University

US Patent
LigandChemical structure of BindingDB Monomer ID 50604033BDBM50604033(CHEMBL5182087 | US20230312529, Compound 6j)
Affinity DataIC50: 17nMAssay Description:Inhibition of PDGFRbeta (unknown origin) by caliper mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Wenzhou Medical University

US Patent
LigandChemical structure of BindingDB Monomer ID 50604033BDBM50604033(CHEMBL5182087 | US20230312529, Compound 6j)
Affinity DataIC50: 23nMAssay Description:The method adopted in the test was Caliper Mobility Shift Assay, which was a detection platform based on the mobility detection technology of microfl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor alpha(Human)
Wenzhou Medical University

US Patent
LigandChemical structure of BindingDB Monomer ID 50604033BDBM50604033(CHEMBL5182087 | US20230312529, Compound 6j)
Affinity DataIC50: 37nMAssay Description:Inhibition of PDGFRalpha (unknown origin) by caliper mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetFibroblast growth factor receptor 2(Human)
Wenzhou Medical University

US Patent
LigandChemical structure of BindingDB Monomer ID 50604033BDBM50604033(CHEMBL5182087 | US20230312529, Compound 6j)
Affinity DataIC50: 89nMAssay Description:The method adopted in the test was Caliper Mobility Shift Assay, which was a detection platform based on the mobility detection technology of microfl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Wenzhou Medical University

US Patent
LigandChemical structure of BindingDB Monomer ID 50604033BDBM50604033(CHEMBL5182087 | US20230312529, Compound 6j)
Affinity DataIC50: 1.00E+3nMAssay Description:The method adopted in the test was Caliper Mobility Shift Assay, which was a detection platform based on the mobility detection technology of microfl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent