BDBM50604114 CHEMBL5180251

SMILES Nc1ccc2ncnc(Nc3ccc4[nH]ccc4c3)c2c1

InChI Key InChIKey=CERWMQWGUSIWNF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50604114   

TargetEpidermal growth factor receptor(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604114BDBM50604114(CHEMBL5180251)
Affinity DataIC50: 0.650nMAssay Description:Inhibition of wild-type EGFR (14 to 721 residues) (unknown origin) by western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604114BDBM50604114(CHEMBL5180251)
Affinity DataIC50: 0.650nMAssay Description:Inhibition of hypoxia-induced HIF1 activation in human T47D cells expressing pGL3 construct after 16 hrs by cell-based luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed