BDBM50604126 CHEMBL5208907

SMILES Nc1ccc2ncnc(Nc3ccc4[nH]cc(Br)c4c3)c2c1

InChI Key InChIKey=SNGCEWRXFPWQJY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50604126   

TargetEpidermal growth factor receptor(Human)
Affiliated Cancer Hospital of University of Electronic Science and Technology of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604126BDBM50604126(CHEMBL5208907)
Affinity DataIC50: 0.740nMAssay Description:Inhibition of hypoxia-induced HIF1 activation in human T47D cells expressing pGL3 construct after 16 hrs by cell-based luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetEpidermal growth factor receptor(Human)
Affiliated Cancer Hospital of University of Electronic Science and Technology of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604126BDBM50604126(CHEMBL5208907)
Affinity DataIC50: 0.740nMAssay Description:Inhibition of wild-type EGFR (14 to 721 residues) (unknown origin) by western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed