BDBM50604170 CHEMBL5193330

SMILES C[C@@H](Oc1ccc2[nH]nc(Nc3c(Cl)cccc3NC(=O)C=C)c2c1)c1c(Cl)cncc1Cl

InChI Key InChIKey=DVRAIMWRJSFRQD-GFCCVEGCSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50604170   

TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Jinan University

Curated by ChEMBL
LigandPNGBDBM50604170(CHEMBL5193330)
Affinity DataIC50:  19nMAssay Description:Inhibition of N-terminal 6His-tagged FGFR4 (unknown orgin) (445 to 753 residues) expressed in Rosetta (NEB) cells using Tyr 04 peptide as substrate i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Jinan University

Curated by ChEMBL
LigandPNGBDBM50604170(CHEMBL5193330)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FGFR3 (unknown orgin) using Tyr 04 peptide as substrate incubated for 1 hr in presence of 75 uM ATP by FRET based Z'-LYTE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Jinan University

Curated by ChEMBL
LigandPNGBDBM50604170(CHEMBL5193330)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FGFR2 (unknown orgin) using Tyr 04 peptide as substrate incubated for 1 hr in presence of 5 uM ATP by FRET based Z'-LYTE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Jinan University

Curated by ChEMBL
LigandPNGBDBM50604170(CHEMBL5193330)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FGFR1 (unknown orgin) using Tyr 04 peptide as substrate incubated for 1 hr in presence of 25 uM ATP by FRET based Z'-LYTE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed