BDBM50604432 CHEMBL5188742

SMILES CC(C)c1cccc2cc(\C=C/c3cccc(c3)C(=O)Nc3ccc(CN4CCN(C)CC4)c(c3)C(F)(F)F)cnc12

InChI Key InChIKey=SWRSEMZTQFCVCQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50604432   

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50604432(CHEMBL5188742)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of human RET kinase using IGF1Rtide as substrate incubated for 40 mins and measured by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed