BDBM50604434 CHEMBL5198379

SMILES COc1c(\C=C/c2cccc(c2)C(=O)Nc2ccc(CN3CCN(C)CC3)c(c2)C(F)(F)F)cnc2ccccc12

InChI Key InChIKey=WEOVEFLSZNJWGH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50604434   

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50604434(CHEMBL5198379)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human RET kinase using IGF1Rtide as substrate incubated for 40 mins and measured by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed