BDBM50604443 CHEMBL5184072

SMILES CN1CCN(Cc2ccc(NC(=O)c3ccc(F)c(\N=N\c4cnc5ccccc5c4)c3F)cc2C(F)(F)F)CC1

InChI Key InChIKey=URVIRFMFFZIHOH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50604443   

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50604443(CHEMBL5184072)
Affinity DataIC50: 11nMAssay Description:Inhibition of human RET kinase using IGF1Rtide as substrate incubated for 40 mins and measured by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed