BDBM50604641 CHEMBL5183674

SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(-c3cn4c5c(sc4n3)CCc3c[nH]cc3-5)cc2)no1

InChI Key InChIKey=OAMPOKDQUZAAKE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50604641   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Palermo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604641BDBM50604641(CHEMBL5183674)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of FLT3 ITD mutant (unknown orgin) by ADP-glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Palermo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604641BDBM50604641(CHEMBL5183674)
Affinity DataIC50: 5.60nMAssay Description:Inhibition of wild type FLT3 (unknown origin) by ADP-glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed