BDBM50604719 CHEMBL1209728

SMILES Cc1c(Br)oc-2c1C(=O)C(=O)c1c3CCCC(C)(C)c3ccc-21

InChI Key InChIKey=AAPTVJGJZCKWPI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50604719   

TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50604719(CHEMBL1209728)
Affinity DataIC50: 5.21E+3nMAssay Description:Inhibition of NLRP3 inflammasome in mouse J774.A1 cells assessed as inhibition of IL-1 beta secretionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Kunming Institute of Botany

Curated by ChEMBL
LigandPNGBDBM50604719(CHEMBL1209728)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human IDO1 assessed as reduction in N-formylkynurenine formation using L-tryptophan as substrate and measured after 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
Kunming Institute of Botany

Curated by ChEMBL
LigandPNGBDBM50604719(CHEMBL1209728)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human TDO assessed as reduction in N-formylkynurenine formation using L-tryptophan as substrate and measured after 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed