BDBM50604733 CHEMBL5206950

SMILES CC(=O)OCc1coc-2c1C(=O)C(=O)c1c3CCC(=O)C(C)(C)c3ccc-21

InChI Key InChIKey=INCOYXMEAVILNC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50604733   

TargetTryptophan 2,3-dioxygenase(Human)
Kunming Institute of Botany

Curated by ChEMBL
LigandPNGBDBM50604733(CHEMBL5206950)
Affinity DataIC50: 670nMAssay Description:Inhibition of recombinant human TDO assessed as reduction in N-formylkynurenine formation using L-tryptophan as substrate and measured after 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Kunming Institute of Botany

Curated by ChEMBL
LigandPNGBDBM50604733(CHEMBL5206950)
Affinity DataIC50: 810nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human HeLa cells assessed as reduction in kynurenine formation using L-tryptophan as substrate by absorbanc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
Kunming Institute of Botany

Curated by ChEMBL
LigandPNGBDBM50604733(CHEMBL5206950)
Affinity DataIC50: 860nMAssay Description:Inhibition of TDO in human HEK293 cells assessed as reduction in kynurenine formation using L-tryptophan as substrate by absorbance based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Kunming Institute of Botany

Curated by ChEMBL
LigandPNGBDBM50604733(CHEMBL5206950)
Affinity DataIC50: 1.73E+3nMAssay Description:Inhibition of recombinant human IDO1 assessed as reduction in N-formylkynurenine formation using L-tryptophan as substrate and measured after 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed