BDBM50605198 CHEMBL5173330

SMILES Nc1nnc(NC2CCN(CC2)c2ccc(NC(=O)CCc3cn(Cc4ccc(OC(F)(F)F)cc4)nn3)nn2)s1

InChI Key InChIKey=LHNYGFIGLPIVBZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50605198   

TargetGlutaminase kidney isoform, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50605198(CHEMBL5173330)
Affinity DataIC50: 1.00E+4nMAssay Description:Allosteric inhibition of human GLS1 using glutamine as substrate incubated for 60 mins by NADH/NADPH-based absorbance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed