BDBM50605208 CHEMBL5172981

SMILES COc1ccc(Cn2cc(CCC(=O)Nc3nnc(s3)N3CCC(CC3)Nc3nnc(NC(=O)Cc4ccccc4)s3)nn2)cc1

InChI Key InChIKey=BOSXAOHRUHHZEO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50605208   

TargetGlutaminase kidney isoform, mitochondrial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50605208(CHEMBL5172981)
Affinity DataIC50: 15nMAssay Description:Allosteric inhibition of human GLS1 using glutamine as substrate incubated for 60 mins by NADH/NADPH-based absorbance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed