BDBM50605449 CHEMBL5195043
SMILES CC(C)n1c(C)nc2c(F)cc(cc12)-c1nc(Nc2cc(Sc3cnc(cn3)N3CCC4(CO[C@@H](C)[C@H]4N)CC3)ccn2)ncc1F
InChI Key InChIKey=CLVKLHYQSCMHQX-QPHCHLROSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50605449
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant N-terminal GST/His6-fusion tagged human CDK4/Cyclin D3 expressed in Sf9 insect cells using 5-FAM-IPTSPITTTYFFFKKK as substr...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:Inhibition of SHP2 (unknown origin) using DiFMUP as substrate incubated for 60 mins followed by substrate addition for 30 mins by microplate reader m...More data for this Ligand-Target Pair