BDBM50605458 CHEMBL5196946

SMILES CCSc1ncc2cc3cnccc3c([N+]([O-])=O)c2n1

InChI Key InChIKey=KXCIPVAPISLTNZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50605458   

TargetSerine/threonine-protein kinase haspin(Human)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50605458(CHEMBL5196946)
Affinity DataIC50:  91nMAssay Description:Inhibition of recombinant human Haspin (470 to 798 residues) expressed in bacterial expression system using ARTKQTARKSTGGKAPRKQLA as substrate measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Rat)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50605458(CHEMBL5196946)
Affinity DataIC50:  515nMAssay Description:Inhibition of recombinant rat DYRK1A (1 to 499 residues ) expressed in bacterial expression system using KKISGRLSPIMTEQ as substrate measured after 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDual specificity protein kinase CLK1(Mouse)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50605458(CHEMBL5196946)
Affinity DataIC50:  148nMAssay Description:Inhibition of recombinant mouse CLK1 expressed in bacteria using GRSRSRSRSRSR as substrate in presence of ATP measured after 30 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed