BDBM50605471 CHEMBL5181620
SMILES COc1ncc2cc3cnccc3c([N+]([O-])=O)c2n1
InChI Key InChIKey=WPPGBVWZGMDXKF-UHFFFAOYSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50605471
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant human Haspin (470 to 798 residues) expressed in bacterial expression system using ARTKQTARKSTGGKAPRKQLA as substrate measur...More data for this Ligand-Target Pair
Affinity DataIC50: 445nMAssay Description:Inhibition of recombinant mouse CLK1 expressed in bacteria using GRSRSRSRSRSR as substrate in presence of ATP measured after 30 mins by ADP-Glo assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Rat)
University of Clermont Auvergne
Curated by ChEMBL
University of Clermont Auvergne
Curated by ChEMBL
Affinity DataIC50: 917nMAssay Description:Inhibition of recombinant rat DYRK1A (1 to 499 residues ) expressed in bacterial expression system using KKISGRLSPIMTEQ as substrate measured after 3...More data for this Ligand-Target Pair
Affinity DataIC50: 578nMAssay Description:Inhibition of human DAPK3 in presence of ATP by kinomescan assayMore data for this Ligand-Target Pair
Affinity DataIC50: 294nMAssay Description:Inhibition of human PLK1 in presence of ATP by kinomescan assayMore data for this Ligand-Target Pair
Affinity DataIC50: 125nMAssay Description:Inhibition of human PLK2 in presence of ATP by kinomescan assayMore data for this Ligand-Target Pair
Affinity DataIC50: 117nMAssay Description:Inhibition of human recombinant PLK3 in presence of ATP by kinomescan assayMore data for this Ligand-Target Pair
Affinity DataIC50: 66nMAssay Description:Inhibition of recombinant human HASPIN (470 to 798 residues) expressed in bacterial expression system in presence of ATP by kinomescan assayMore data for this Ligand-Target Pair