BDBM50605577 CHEMBL5191702

SMILES FC(F)c1ccc(SCc2c[nH]c(=O)c(=O)[nH]2)cc1

InChI Key InChIKey=DLHGRKAZQBZUNQ-UHFFFAOYSA-N

Data  6 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50605577   

TargetD-amino-acid oxidase(Homo sapiens (Human))
Schr£Dinger

Curated by ChEMBL
LigandPNGBDBM50605577(CHEMBL5191702)
Affinity DataIC50:  72nMAssay Description:Inhibition of recombinant full length human DAO preincubated with compound for 20 mins measured after 4 hrs by Amplex red and horseradish peroxidase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Schr£Dinger

Curated by ChEMBL
LigandPNGBDBM50605577(CHEMBL5191702)
Affinity DataEC50:  620nMAssay Description:Inhibition of full length human DAO transfected in CHO-K1 cells incubated for 30 mins by Amplex red and horseradish peroxidase based fluorescence ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetD-amino-acid oxidase(Mus musculus)
Schr£Dinger

Curated by ChEMBL
LigandPNGBDBM50605577(CHEMBL5191702)
Affinity DataEC50:  620nMAssay Description:Inhibition of full length mouse DAO transfected with CHO-K1 cells incubated for 30 mins by Amplex red and horseradish peroxidase based fluorescence a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Schr£Dinger

Curated by ChEMBL
LigandPNGBDBM50605577(CHEMBL5191702)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human PPAR gamma NHR incubated for 120 mins by scintillation counting based radiometry assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Schr£Dinger

Curated by ChEMBL
LigandPNGBDBM50605577(CHEMBL5191702)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant 5-LOX incubated for 5 mins by fluorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Schr£Dinger

Curated by ChEMBL
LigandPNGBDBM50605577(CHEMBL5191702)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human adenosine A3 GPCR incubated for 120 mins by scintillation counting based radiometry assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Schr£Dinger

Curated by ChEMBL
LigandPNGBDBM50605577(CHEMBL5191702)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of GR human glucocorticoid NHR incubated for 360 mins by scintillation counting based radiometry assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Schr£Dinger

Curated by ChEMBL
LigandPNGBDBM50605577(CHEMBL5191702)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed