BDBM50606011 CHEMBL5191892

SMILES C[C@H](NC(=O)c1ccc-2cc1OCCOCCNc1ccn3ncc-2c3n1)c1ccncc1

InChI Key InChIKey=FFVXISWLYSJERX-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50606011   

TargetSerine/threonine-protein kinase 17A(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50606011(CHEMBL5191892)
Affinity DataKd:  9nMAssay Description:Binding affinity to human N-terminal His-tagged/ TEV cleavage fused DRAK1 (39 to 369 residues) expressed in Escherichia coli by isothermal titration ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase 17A(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50606011(CHEMBL5191892)
Affinity DataIC50: 15nMAssay Description:Inhibition of human N-terminal His-tagged/ TEV cleavage fused DRAK1 (39 to 369 residues) expressed in Escherichia coli using KKLNRTLSFAEPG peptide as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase 17A(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50606011(CHEMBL5191892)
Affinity DataIC50: 70nMAssay Description:Inhibition of human N-terminal His-tagged/ TEV cleavage fused DRAK1 (39 to 369 residues) transfected in HEK293T cells using NanoBRET NanoGlo as subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed