BDBM50606480 CHEMBL5219231

SMILES NC1CC1c1ccc(NC(=O)CCCc2ccccc2)cc1

InChI Key InChIKey=CRCCUAFDUKKGDY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50606480   

TargetLysine-specific histone demethylase 1A(Human)
Menoufia University

Curated by ChEMBL
LigandPNGBDBM50606480(CHEMBL5219231)
Affinity DataIC50: 360nMAssay Description:Inhibition of N-terminal GST tagged LSD1 (residues 171 - 852) (unknown origin) overexpressed in Escherichia coli using ARTK(Me)2QTARKSTGGKAPRKQLAas s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Menoufia University

Curated by ChEMBL
LigandPNGBDBM50606480(CHEMBL5219231)
Affinity DataIC50: 400nMAssay Description:Inhibition of human recombinant LSD1 using fluorogenic ADHP as substrate preincubated for 30 mins followed by substrate addition measured after 10 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 1(Human)TBA
LigandPNGBDBM50606480(CHEMBL5219231)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human recombinant HDAC1 using fluorogenic HDAC substrate preincubated for 30 mins followed by substrate addition and measured after 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed