BDBM50606733 CHEMBL5218988
SMILES CC(C)CC1(C)CN(c2c1ncnc2N)c1ccc2oc(N)nc2c1
InChI Key InChIKey=JGRISWOXHZGZPV-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50606733
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
University Of Hradec Kralove
Curated by ChEMBL
University Of Hradec Kralove
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Binding affinity to mTOR (unknown origin) assessed as inhibition constant measured after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
TargetTarget of rapamycin complex subunit LST8(Homo sapiens)
University Of Hradec Kralove
Curated by ChEMBL
University Of Hradec Kralove
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of mTORC1 in human A-431 cells assessed as phosphorylated S6RP level incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Homo sapiens)
University Of Hradec Kralove
Curated by ChEMBL
University Of Hradec Kralove
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Inhibition of mTORC2 in human A-431 cells assessed as phosphorylated AKT level incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair