BDBM50607441 CHEMBL5220960

SMILES CN1CCN(CC1)c1ccc(CN(CC(C)(C)C)c2nccc(n2)C#N)cc1

InChI Key InChIKey=CROHKCAOPCLRAC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50607441   

TargetCathepsin K(Human)
Shandong New Time Pharmaceutical

US Patent
LigandPNGBDBM50607441(CHEMBL5220960 | US20250145576, Compound K1)
Affinity DataIC50: 55nMAssay Description:Cathepsin K (CTSK, EC 3.4.22.38) is a lysosomal cysteine protease, participates in osteoclastic bone remodeling and resorption, and can further degra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetCathepsin K(Human)
Shandong New Time Pharmaceutical

US Patent
LigandPNGBDBM50607441(CHEMBL5220960 | US20250145576, Compound K1)
Affinity DataIC50: 62nMAssay Description:Inhibition of Cathepsin K (unknown origin) assessed as inhibition of AFC release using sequence LR labelled with AFC as substrate by fluorescence bas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCathepsin S(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50607441(CHEMBL5220960 | US20250145576, Compound K1)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of Cathepsin S (unknown origin) assessed as inhibition of AFC release using sequence VVR labelled with AFC as substrate by fluorescence ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCathepsin B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50607441(CHEMBL5220960 | US20250145576, Compound K1)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Cathepsin B (unknown origin) assessed as inhibition of AFC release using sequence RR labelled with AFC as substrate by fluorescence bas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed