BDBM50608696 CHEMBL5268949

SMILES Cc1ccc(N\N=C2\C(N)=NN(C2=N)c2ccc(cc2)S(N)(=O)=O)cc1

InChI Key InChIKey=LHJHSVYCWBHMQI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50608696   

TargetProstaglandin G/H synthase 2(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50608696(CHEMBL5268949)
Affinity DataIC50: 670nMAssay Description:Inhibition of COX-2 (unknown origin) by EIA kit methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50608696(CHEMBL5268949)
Affinity DataIC50: 670nMAssay Description:Inhibition of COX-2 (unknown origin) using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50608696(CHEMBL5268949)
Affinity DataIC50: 1.92E+3nMAssay Description:Inhibition of 5-LOX (unknown origin) after 5 mins by colorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50608696(CHEMBL5268949)
Affinity DataIC50: 1.92E+3nMAssay Description:Inhibition of 5-LOX (unknown origin) by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed