BDBM50609011 CHEMBL5287921

SMILES CC[C@@H]1CN2CCc3c([nH]c4cccc(O[C@@H]5O[C@H](C(=O)O)[C@@H](O)[C@H](O)[C@H]5O)c34)[C@@H]2C[C@@H]1/C(=C\OC)C(=O)OC

InChI Key InChIKey=PRYHOGCYPICMAJ-UHFFFAOYSA-N

Data  3 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50609011   

TargetKappa-type opioid receptor(Mouse)
University of Health Sciences & Pharmacy and Washington University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50609011BDBM50609011(CHEMBL5287921)
Affinity DataEC50:  1.14E+3nMAssay Description:Agonist activity at mouse KOR expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 60 mins by scintillati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Mouse)
University of Health Sciences & Pharmacy and Washington University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50609011BDBM50609011(CHEMBL5287921)
Affinity DataKi:  1.27E+3nMAssay Description:Displacement of [125]IBNtxA from mouse KOR stably expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Mouse)
University of Health Sciences & Pharmacy and Washington University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50609011BDBM50609011(CHEMBL5287921)
Affinity DataKi:  1.68E+3nMAssay Description:Displacement of [125]IBNtxA from mouse MOR stably expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetDelta-type opioid receptor(Mouse)
University of Health Sciences & Pharmacy and Washington University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50609011BDBM50609011(CHEMBL5287921)
Affinity DataKi:  3.24E+3nMAssay Description:Displacement of [125]IBNtxA from mouse DOR stably expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Mouse)
University of Health Sciences & Pharmacy and Washington University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50609011BDBM50609011(CHEMBL5287921)
Affinity DataEC50:  5.78E+3nMAssay Description:Agonist activity at mouse MOR expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 60 mins by scintillati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed