BDBM50609570 CHEMBL5269021

SMILES COc1cc(C)c(Cl)cc1S(=O)(=O)Nc1ccc2N(CCCc2c1)C(=O)c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=LQBVXWVKJXJFSJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50609570   

TargetGlucocorticoid receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50609570(CHEMBL5269021)
Affinity DataIC50: 300nMAssay Description:Modulation of glucocorticoid receptor (unknown origin) transfected in human HeLa cells assessed as transrepression by measuring inhibition of TNF-alp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetGlucocorticoid receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50609570(CHEMBL5269021)
Affinity DataIC50: 2.22E+3nMAssay Description:Binding affinity to glucocorticoid receptor (unknown origin) by Lanthascreen TR-FRET competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetGlucocorticoid receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50609570(CHEMBL5269021)
Affinity DataIC50: 3.33E+3nMAssay Description:Modulation of glucocorticoid receptor (unknown origin) transfected in human HeLa cells assessed as transrepression by measuring inhibition of PMA-ind...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed