BDBM50609606 CHEMBL5279491

SMILES COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ncc(C#C)c(n1)-c1cn2CCCc3cccc1c23

InChI Key InChIKey=UVAQIYRGODMQEF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50609606   

TargetEpidermal growth factor receptor(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50609606(CHEMBL5279491)
Affinity DataIC50: 42nMAssay Description:Inhibition of EGR-induced EGFR phosphorylation in human A549 cells pretreated for 2 hrs followed by EGF stimulation by immune assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed