BDBM50609811 CHEMBL5288280
SMILES COc1ccc(OC)c(c1)-n1nnc(C(=O)Nc2cc(ccc2OCCC(C)C)C(C)(C)C)c1C
InChI Key InChIKey=SCIFKNPYAZAVFV-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50609811
TargetNuclear receptor subfamily 1 group I member 2(Human)
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of BODIPY FL vindoline binding to recombinant human GST-tagged PXR LBD (111 to 434 residues) expressed in baculovirus infected insect cell...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 2(Human)
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Antagonist activity at human PXR in human HepG2 cells co-expressing luciferase gene under control of CYP3A4 promoter assessed as inhibition in rifamp...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 2(Human)
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 42nMAssay Description:Inverse agonist activity at human PXR in human HepG2 cells co-expressing luciferase gene under control of CYP3A4 promoter assessed as inhibition of r...More data for this Ligand-Target Pair