BDBM50609813 CHEMBL5281952

SMILES CCCC(C)Oc1ccc(cc1NC(=O)c1nnn(c1C)-c1cc(C)ccc1OC)C(C)(C)C

InChI Key InChIKey=UOXKTTLWMUQDFC-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50609813   

TargetNuclear receptor subfamily 1 group I member 2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50609813(CHEMBL5281952)
Affinity DataIC50:  6.90nMAssay Description:Antagonist activity at human PXR in human HepG2 cells co-expressing luciferase gene under control of CYP3A4 promoter assessed as inhibition in rifamp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetNuclear receptor subfamily 1 group I member 2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50609813(CHEMBL5281952)
Affinity DataIC50:  18nMAssay Description:Inhibition of BODIPY FL vindoline binding to recombinant human GST-tagged PXR LBD (111 to 434 residues) expressed in baculovirus infected insect cell...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB