BDBM50609814 CHEMBL5284539
SMILES CCC[C@H](C)Oc1ccc(cc1NC(=O)c1nnn(c1C)-c1cc(OC)ccc1OC)C(C)(C)C
InChI Key InChIKey=LCZDEXFSZLWZDC-KRWDZBQOSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50609814
Affinity DataIC50: 6nMAssay Description:Inhibition of BODIPY FL vindoline binding to recombinant human GST-tagged PXR LBD (111 to 434 residues) expressed in baculovirus infected insect cell...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Antagonist activity at human PXR in human HepG2 cells co-expressing luciferase gene under control of CYP3A4 promoter assessed as inhibition in rifamp...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inverse agonist activity at human PXR in human HepG2 cells co-expressing luciferase gene under control of CYP3A4 promoter assessed as inhibition of r...More data for this Ligand-Target Pair