BDBM50610545 CHEMBL5266286

SMILES COc1ccccc1NC(=O)C1CCN(CC1)C(=O)c1ccccc1

InChI Key InChIKey=XRTYGCKYPFSQNR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50610545   

TargetAcetylcholinesterase(Human)
University of Aveiro

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50610545BDBM50610545(CHEMBL5266286)
Affinity DataIC50: 8.5nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
University of Aveiro

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50610545BDBM50610545(CHEMBL5266286)
Affinity DataIC50: 8.5nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substratE incubated for 20 mins by DTNB reagent based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetBeta-secretase 1(Human)
University of Aveiro

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50610545BDBM50610545(CHEMBL5266286)
Affinity DataIC50: 19nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetBeta-secretase 1(Human)
University of Aveiro

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50610545BDBM50610545(CHEMBL5266286)
Affinity DataIC50: 19nMAssay Description:Inhibition of human BACE-1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed