BDBM50610746 CHEMBL5286760

SMILES CCCCCCCCCCCCCC(=S)NCCCC[C@H](NS(C)(=O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O

InChI Key InChIKey=NPHRYTDSZLSLKK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50610746   

TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Minia University

Curated by ChEMBL
LigandPNGBDBM50610746(CHEMBL5286760)
Affinity DataIC50: 70nMAssay Description:Inhibition of human SIRT2 deacetylase activity using QPKKac as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Minia University

Curated by ChEMBL
LigandPNGBDBM50610746(CHEMBL5286760)
Affinity DataIC50: 70nMAssay Description:Inhibition of recombinant human C-terminal His-tagged Sirt2 (50 to 356 residues) expressed in Escherichia coli using QPKKac as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Minia University

Curated by ChEMBL
LigandPNGBDBM50610746(CHEMBL5286760)
Affinity DataIC50: 90nMAssay Description:Inhibition of human SIRT2 demyristoylation activity using ETDKac as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Minia University

Curated by ChEMBL
LigandPNGBDBM50610746(CHEMBL5286760)
Affinity DataIC50: 120nMAssay Description:Inhibition of recombinant human C-terminal His-tagged Sirt2 (50 to 356 residues) expressed in Escherichia coli using r ETDKmyr as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed