BDBM50610824 CHEMBL5268966

SMILES OC(=O)c1ccc(cn1)C#Cc1ccccc1NS(=O)(=O)c1cccc2cccnc12

InChI Key InChIKey=CSXPKHMTZGKCRO-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50610824   

TargetMonocarboxylate transporter 4(Homo sapiens (Human))TBA
LigandPNGBDBM50610824(CHEMBL5268966)
Affinity DataKi:  37nMAssay Description:Binding affinity to full-length C-terminal GFP-tagged human MCT4 incubated for 1 hrs by fluorescence cross-correlation spectroscopy analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMonocarboxylate transporter 4(Homo sapiens (Human))TBA
LigandPNGBDBM50610824(CHEMBL5268966)
Affinity DataIC50:  1.77E+5nMAssay Description:Inhibition of human MCT4 in human MDA-MB-231 cells assessed as inhibition of lactate efflux preincubated for 30 mins followed by D(+)glucose and meas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMonocarboxylate transporter 4(Homo sapiens (Human))TBA
LigandPNGBDBM50610824(CHEMBL5268966)
Affinity DataIC50:  215nMAssay Description:Binding affinity to full-length C-terminal GFP-tagged human MCT4 incubated for 1 hrs by fluorescence cross-correlation spectroscopy analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed