BDBM50610827 CHEMBL5287780

SMILES Cc1ccnc2c(cccc12)S(=O)(=O)Nc1ccccc1C#Cc1ccc(nc1)C(O)=O

InChI Key InChIKey=KEYTVFBKDMLYPC-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50610827   

TargetMonocarboxylate transporter 4(Homo sapiens (Human))TBA
LigandPNGBDBM50610827(CHEMBL5287780)
Affinity DataKi:  32nMAssay Description:Binding affinity to full-length C-terminal GFP-tagged human MCT4 incubated for 1 hrs by fluorescence cross-correlation spectroscopy analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMonocarboxylate transporter 4(Homo sapiens (Human))TBA
LigandPNGBDBM50610827(CHEMBL5287780)
Affinity DataIC50:  2.09E+5nMAssay Description:Inhibition of human MCT4 in human MDA-MB-231 cells assessed as inhibition of lactate efflux preincubated for 30 mins followed by D(+)glucose and meas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMonocarboxylate transporter 4(Homo sapiens (Human))TBA
LigandPNGBDBM50610827(CHEMBL5287780)
Affinity DataIC50:  154nMAssay Description:Binding affinity to full-length C-terminal GFP-tagged human MCT4 incubated for 1 hrs by fluorescence cross-correlation spectroscopy analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed